Nikki Glaser (/ˈɡleɪsər/; born June 1, 1984) is an American stand-up comedian, actress, and television host. She hosted the television series Not Safe with Nikki Glaser, which premiered on Comedy Central in 2016. She starred in the 2022 reality show Welcome Home Nikki Glaser? on E! She hosted the reality TV dating shows Blind Date (2019) on Bravo and FBoy Island (2021–2023) on HBO Max and The CW and its spinoff Lovers and Liars on The CW. She also hosted the 2025 Golden Globe Awards, which made her the first solo female host in Golden Globes history.

She has acted in the Amy Schumer comedy films Trainwreck (2015) and I Feel Pretty (2018) and has appeared on shows such as Inside Amy Schumer and A.P. Bio. She has competed in competition shows such as Dancing with the Stars (2018) and The Masked Singer (2022). She has also participated in the roasts of Rob Lowe (2016), Bruce Willis (2018), Alec Baldwin (2019), and Tom Brady (2024). She has received nominations at the Critics' Choice Television Awards, Golden Globe Awards, Grammy Awards, and Primetime Emmy Awards.