Charlotte Vandermeersch (born 11 November, 1983; Oudenaarde) is a Belgian actress and director.

Charlotte Vandermeersch graduated in 2005 from the Herman Teirlinck Institute in Antwerp as a Master in Dramatic Art. She has played in numerous theater productions with, among others, SKaGeN, Wunderbaum and Abattoir Fermé. Together with Maaike Neuville she made her own theater production "The Kiss of the Spider Woman.