Penelope Pitsouli (Greek: Πηνελόπη Πιτσούλη, Thessaloniki, October 3, 1947) is a Greek actress

She was born in Thessaloniki where she grew up. After finishing school, she went to the Philosophy School, but eventually re-took the Panhellenic exams and passed the Kindergarten Department in Ioannina. Finally, at the age of 19, she decided to become an actress. Thus, she began her studies at the Dimitris Konstantinidis Drama School, from which she graduated a few years later.