David Lewis (October 19, 1916 – December 11, 2000) was an American actor, born in Pittsburgh, Pennsylvania. He was best known for being the original actor to portray Edward Quartermaine from 1978 to 1993 on the American soap opera General Hospital.

Lewis was a pioneering actor in television, his first televised role occurring in 1949 on the show Captain Video and His Video Rangers. His credits include appearing in seven episodes of Perry Mason and in the recurring role of Warden Crichton in Batman. Lewis appeared on daytime T.V., making his soap debut on Love of Life as a murderer and later playing patriarch Henry Pierce on Bright Promise. Brief guest stints on The Young and the Restless and Days of Our Lives followed.