Chloe Webb (born June 25, 1956) is an American actress.

Webb was born in Greenwich Village, Manhattan, New York. Her New York theater debut was in the original cast of the long-running musical satire Forbidden Broadway. She received Best Actress award from the National Society of Film Critics for her film debut in the 1986 cult classic feature film Sid and Nancy, which was based on the relationship of the Sex Pistols bassist, Sid Vicious, and his girlfriend Nancy Spungen. Many independent films followed, most recently the film Repo Chick, directed by Alex Cox.