Giuseppe De Santis (11 February 1917 – 16 May 1997) was an Italian film director. One of the most idealistic neorealist filmmakers of the 1940s and 1950s, he wrote and directed films punctuated by ardent cries for social reform.

In 1942, De Santis collaborated on the script for Ossessione, Luchino Visconti's debut film, which is usually considered one of the first neo-realist films.