Terrylene Sacchetti (born February 5, 1967) is a deaf actress from Chicago, Illinois. She graduated from the Model Secondary School for the Deaf in 1985.

Her most well known work in the film industry is for Natural Born Killers (1994), After Image (2001) and Listen Carefully (1991). She is also known in the deaf community for her advocacy for the right to sign language and early intervention for deaf infants.