Kali Reis (born August 24, 1986) is an American professional boxer and actress. She is a former world champion in two weight classes, having held the WBC female middleweight title in 2016 and the WBA, WBO, and IBO female light welterweight titles between 2020 and 2022. She also challenged Cecilia Brækhus for the undisputed female welterweight title in 2018.

In 2021, Reis made her acting debut as the star of the American thriller film Catch the Fair One. For her performance as a boxer endeavouring to rescue her missing sister, she was nominated for the Independent Spirit Award for Best Female Lead. She has since starred in the mystery series True Detective: Night Country (2024), for which she received nominations for a Primetime Emmy Award, a Golden Globe Award, and a Critics' Choice Award.