Luisita Barzizza, better known as Isa Barzizza (Sanremo, Italy 22 November 1929 – Palau, Italy 28 May 2023), was an Italian actress. She enjoyed a very long acting career, spanning from the second half of the 1940s to the first half of the 2010s.

The daughter of orchestra conductor Pippo Barzizza and Tatina Salesi, elder sister of director Renzo Barzizza and cousin of the appearance Anna Maria Salesi, she established herself throughout her career as a performer in revue theatre, cinema and television, becoming one of the earliest television personalities in Italy alongside Totò.