Shirley Henderson (born 24 November 1965) is a Scottish actress. Her accolades include two Scottish BAFTAs, a VFCC Award and an Olivier Award, and BAFTA, BIFA, London Critics' Circle, Chlotrudis, Gotham, and Canadian Screen Award nominations.

Henderson's film roles include Gail in Trainspotting (1996) and its 2017 sequel, Jude in the Bridget Jones films (2001–2025), and Moaning Myrtle in Harry Potter and the Chamber of Secrets (2002) and Harry Potter and the Goblet of Fire (2005). Her other notable credits include Rob Roy (1995), Wonderland (1999), Topsy-Turvy (1999), 24 Hour Party People (2002), Wilbur Wants to Kill Himself (2002), Intermission (2003), American Cousins (2003), Frozen (2005), Marie Antoinette (2006), Miss Pettigrew Lives for a Day (2008), Life During Wartime (2009), Meek's Cutoff (2010), Anna Karenina (2012), Filth (2013), Okja (2017), Never Steady, Never Still (2017), and Stan & Ollie (2018).