Christos Nikou (Greek: Χρήστος Νίκου, born 1984; Athens) is a Greek film director and screenwriter. His short film Km (2012) participated in over 40 international film festivals, including Rotterdam, Stockholm, Palm Springs, Sydney, Tallinn Black Nights, and Interfilm Berlin. It won him the Best Short Film Prize at the Motovun Film Festival of Croatia.

For the past ten years, he has worked as an assistant director on the feature films Dogtooth (Yorgos Lanthimos) and Before Midnight (Richard Linklater), as well as 4 Black Suits, Nobody, Christmas Tango, A Greek Type of Problem, 7 Kinds of Wrath, and Approach. His first feature film with him in the directing seat was Apples (2020).