Spyros Kalogirou (Greek: Σπύρος Καλογήρου, Kypseli, 3 November 1922 - Athens, 27 June 2009) was a Greek theatre and film actor, best known for his villainous roles on the big screen. His trembling voice and fierce appearance were characteristic.

He acted in many films, both on television and in cinema, and when he played such roles he was very convincing. He also participated in many theatrical performances but did not have many collaborations with his wife, as she was at the National Theater and he was more involved with independent theater. After the '80s they formed their own troupe, staged performances and toured.