Sasha Luss was born on 6 June 1992 in Magadan and moved to Moscow at a young age. At the age of fourteen, Sasha signed with IQ Models in Moscow. Shortly after she turned sixteen years old, Sasha walked in her very first fashion show for Alena Akhmadullina during Moscow Fashion Week Spring/Summer 2008.

Sasha quickly shot to fame in the Russian fashion industry and was featured in multiple issues of Vogue Russia and L'Officiel Russia in 2008. She signed with DNA Model Management who flew her to Europe and New York, where she walked in fashion shows for designers such as DKNY and Antonio Marras. Despite these successful bookings, her career failed to take off and she returned to Russia to complete her education. Sasha decided to sign with Elite Model Management in Paris and Women Management in Milan as a development model and in 2011 left her mother agency, IQ Models, to join Avant Models.