Santhanam is an Indian film actor who has predominantly appeared in Tamil films as a comedian.

Beginning his career as a comedian on television shows, he rose to fame through his performances in Vijay TV's Lollu Sabha enacting the lead role in spoofs of Tamil films. He was subsequently given a chance by actor Silambarasan to feature in a supporting role in Manmadhan (2004) and then was signed on to appear in a host of films, notably winning good reviews for his work in Sachien (2005) and Polladhavan (2007).