Sarah Margaret Qualley (/ˈkwɔːli/ KWAW-lee; born October 23, 1994) is an American actress. A daughter of actress Andie MacDowell, she trained as a ballet dancer in her youth. She made her acting debut in the 2013 drama film Palo Alto. She gained recognition for her supporting role in the HBO drama series The Leftovers (2014–2017).

Qualley appears in the films The Nice Guys (2016), Death Note (2017) and Once Upon a Time in Hollywood (2019), and the video games Death Stranding (2019) and Death Stranding 2: On the Beach (2025). She received praise and nominations at the Primetime Emmy Awards for her portrayal of Ann Reinking in the FX biographical miniseries Fosse/Verdon (2019) and for the title role in the Netflix drama miniseries Maid (2021); she also received a  Golden Globe Award nomination for the latter. Qualley has since appeared in Yorgos Lanthimos's films Poor Things (2023) and Kinds of Kindness (2024), and earned a second Golden Globe nomination for her performance in the body horror film The Substance (2024). In 2026, she co-starred with Jacob Elordi, Guy Pearce, and Josh Brolin in director Ridley Scott's post-apocalyptic drama The Dog Stars.