Zoe Perry (born September 26, 1983) is an American actress. The daughter of actors Laurie Metcalf and Jeff Perry, she made her film debut in Deception (2008) and had a supporting role in the independent drama film The Loss of a Teardrop Diamond (2008).

After recurring roles as Jane on The Family (2016) and Samantha Ruland on Scandal (2017), Perry had her breakout as Mary Cooper on the CBS sitcom Young Sheldon (2017–24). The role, which was played by her mom Laurie Metcalf on The Big Bang Theory, earned Perry a nomination for the Critics' Choice Television Award for Best Supporting Actress in a Comedy Series in 2019. She reprised the role on the spin-off series Georgie & Mandy's First Marriage (2024–present).