Sam Esmail (born September 17, 1977) is an American film and television producer, director, and screenwriter who runs Esmail Corp. He is best known as the creator, writer, and director of the award-winning USA Network television series Mr. Robot (2015–2019), starring Rami Malek. He wrote and directed the feature films Comet (2014) and Leave the World Behind (2023). He produced and directed the first season of the acclaimed Amazon Prime Video psychological thriller Homecoming (2018–2020), starring Julia Roberts and Janelle Monáe, and produced USA's Briarpatch (2020), Starz's Gaslit (2022), and Peacock's Angelyne (2022) and The Resort (2022).

Esmail's work often centres on alienation, technology, and American society.