Moustapha Alassane (1942–17 March 2015) was a Nigerien filmmaker.

Born in 1942 in N’Dougou (Niger), Moustapha Alassane graduated in mechanics. However, in the Rouch IRSH in Niamey he learned the cinematographic technique and thereafter became one of its main proponents. Jean Rouch provided for Alassane's education and accommodation in Canada, where he met the famous Norman McLaren, who taught him about animation.