Virginie Lemoine (born 26 February 1961) is a French actress and comedian.

Virginie Lemoine attended acting school at the Conservatory in Rouen. From 1982 to 1990, she played theater on stage, and regularly participated in the show Ainsi font font font, hosted by Jacques Martin on France 2. In 1991, she became a radio host in the show C'est aussi bien à l'ombre and Le Vrai Faux Journal. In 1992, Laurent Gerra and Lemoine Virginie became a comedy duo and appeared in many television shows and became very popular. In 1997, they won the Molière Award for Best one man show for their show on the Théâtre Déjazet.