Jean Byron (born Imogene Audette Burkhart; December 10, 1925 – February 3, 2006, Height 5 feet 9 inches [1.75 meters]) was an American film, television, and stage actress. She was best known for the role of Natalie Lane, Patty Lane's mother in the sitcom The Patty Duke Show.

Byron was born in Paducah, Kentucky, and raised in Louisville. She began her career as a singer on radio, and then moved to Los Angeles to pursue an acting career. She made her film debut in 1952's Voodoo Tiger. She appeared in several other films, including The Magnetic Monster (1953), Serpent of the Nile (1953), and The Opposite Sex (1956).