Jones-Quartey created multiple Web Cartoonists' Choice Award-winning webcomic RPG World. He was also a founding member of the now-defunct "bagofchips" group, a collective of web cartoonists including Aaron Farber, Meredith Gran, Josh Mirman, and David McGuire. He is also the co-creator of the web animation series and comedy hip-hop duo nockFORCE, rapping under the stage name 'effnocka' along with audio specialist Jim Gisriel.

He also served as a storyboard supervisor and revisionist for Adventure Time and storyboard artist for Secret Mountain Fort Awesome. His first job in the business was on The Venture Bros.. He supplies the voice of Wallow in Bravest Warriors and was the supervising director and co-developer of the Cartoon Network series Steven Universe.