Born and raised in Chicago, Lisa Joyce received her BFA in Acting from the Theater School at DePaul University. She received a Joseph Jefferson nomination for her performance in Adam Rapp's "Red Light Winter", which premiered at the Steppenwolf Theater Company before transferring off-Broadway and being named a finalist for The Pulitzer Prize.

Lisa made her West End/Broadway debut in "La Bete", starring Mark Rylance and David Hyde Pierce, and toured nationally, alongside Cherry Jones in the Tony Award-winning production of "Doubt".