Natasha Leggero (born March 26, 1974) is an American actress and comedian from Rockford, Illinois. She was a frequent roundtable panelist on friend Chelsea Handler's late-night talk show Chelsea Lately.

Her stand-up television appearances include performances on The Tonight Show with Jay Leno, The Late Late Show with Craig Ferguson, Last Call with Carson Daly, and she has appeared on multiple Comedy Central stand-up programs, as well as their animated show Ugly Americans, where she voiced Callie Maggotbone.