Attended Carnegie Tech (now Carnegie-Mellon University) as a playwriting major. Barbara Bosson (his second wife), Michael Tucker, Bruce Weitz and Charles Haid were classmates; he and Tucker drove cross-country to Hollywood for full-time jobs at Universal, where Bochco would remain for 12 years.

In 1978, he moved to MTM Enterprises, who after several attempts gave him carte Blanche to create a show similar to Fort Apache the Bronx (1981) (Hill Street Blues (1981)). In 1985, MTM fired him, in part for his inability to keep HSB on budget. After creating L.A. Law (1986) and Doogie Howser, M.D. (1989) for NBC, he struck a $15M deal with ABC in 1987 to create 10 series pilots over 10 years.