
Before becoming known to millions as Granny on The Beverly Hillbillies (1962), Irene Ryan was already an established vaudeville, radio and movie actress, though not as famous prior to her television stint. She accompanied Bob Hope on his famous military tours and she was known as "the gal who makes Bob Hope laugh." After being cast as Granny, she became famous overnight. When the Hillbillies ended, she co-starred in the Broadway musical 'Pippin' with Ben Vereen. Unfortunately, despite wonderful reviews from critics, Ryan took ill, was discovered to have an inoperable brain tumor and died soon after at the age of 70.
Biography from Wikipedia, CC BY-SA. Credits and photos from TMDB.
The titles people know Irene from.
IMDb rating of each title on Cineora, by year.
1 episode

as Granny (uncredited)
1 episode
as Granny · 2 episodes
as Granny · 274 episodes
1 episode

as Nora Finney

2 episodes

as Eunice Johnson
1 episode

as Martha Henderson · 1 episode

as Miss Stapleton

1 episode

as Miss Clay

1 episode

as Mrs. Bryant · 1 episode

as Mrs. Mullin
as Southern Belle at the Bar (uncredited)

as Mrs. Shaw
as Mary

as Opal Cheever
as Irate Wife (uncredited)

as Molly
as Mrs. Mary Wernecke

as Irene / Cleopatra
as Irene
as Irene Ryan
as Irene
as Irene
The people who keep turning up in Irene’s titles.