Manolis Destounis (Athens, November 19, 1937-) is a Greek actor.

He is a graduate of the Athens School of Commerce. He studied at the Athens Drama School G. Theodosiadis (graduated in 1965), at the "British Drama School" in London and at the Rallou Manou dance school. He made his debut in 1964 with the "Arma Theatrou" troupe. Collaborations with well-known troupes such as those of Dimitris Myrat, Mimis Fotopoulos, Sofia Vembo, etc. followed. In 1966 he took his first steps in cinema with the film A Ship Papadopoulos (1966). His career in television is also noteworthy, with participation in plays and series. He occasionally staged his own theatrical productions and was a conductor for various theatrical groups. He directed five films. He also developed an activity in the field of music, as a composer, singer and lyricist. A close relative of the former actor of the National Theatre, Ilias Destounis.