Leopoldo Ganal Salcedo Sr. (March 12, 1912 – June 11, 1998) was a Filipino film actor dubbed as "The Great Profile" who specialized in portraying dramatic heroes.

In 1950, Salcedo formed his own production company, Leopoldo Salcedo Productions, which produced such films as Dalawang Bandila (1950), Talampasan (1953), and Highway 54 (1953). Many of Salcedo's post-war choices in roles tended towards socially relevant dramas. He had intended to produce a film on the life of the Hukbalahap leader Luis Taruc. Films such as Bisig ng Manggagawa (1951) and Batong Buhay (Sa Central Luzon) (1950) dealt with labor and agrarian strife.