Adapted from the successful play, the film takes place in 19th-century Japan, where a war between demons and their slayers is fought. Izumo, a kabuki actor with a demon-slaying past, meets and falls in love with Tsubaki. However, something is not right, as mysterious marks appear on her body as time progresses. At the same time, it is announced that Ashura, the queen of all demons, will be resurrected and bring destruction to the universe.